Build 464A is released.

1. Raster Paintbrush dialog update.

Build 464 is released.

 1. Spine Disc compression (Jacobian map) workflow documentation created.

2. Corrected the IPP (image position patient) after  the 4D volume crop.

3. Implemented ABT subtest for the FLAIR SYNTH  Training Reg\Norm.

4. Implemented Unet3D variant using the Pool\Unpool with indices (instead of customary MaxPool).

5. Implemented Volume>AdvanceTo>Timepoint of Max Signal

6. Allowed PET volumes to be of INT type too, so some workflows now enabled.

7.  PET-FDG motion correction : changed default motion correction parameters.

8. LayerControl dialog:  fixed the defect when the SelectedItem was outside the list window, then after

any operation it would jump to display the selected item, etc.

9. Implemented Radial Forward AutoFocus4D method, specifically to reduce jittering issues in FDG motion correction.

10.  WorkFlow>Brain FDG-DCE:  implemented an automatic Target ROI calculation. User typically

advances to about 1000 sec, Chooses 4D PET, Brain Atlas. Mask is automatically produced.

11. Layer Control dialog: made it more intuitive by splitting the Remove Active\Unmarked functions.

12. AutoFocus4D dialog:  now displays the current Dynamic Index used as the Target of registration.

13. Combine WMSEED {X,Y,Z}  GUI function into a single WMseed menu item.

14. Fixed bug when all 4D layers are removed, the current timepoint is still >0.

15. Fixed bug in WMseed and EdgeWave function when there are both 3D and 4D layers, current T>0 operation is called on 3D layer. Crash due to the incorrect timepoinyt.

16. Replaced URAL naming on GUI to "Normalized Gradient Field".

Build 463 is released.

 1. Update the FLEXR3D dialog box.

2. Update FLEXR3D User documentation

3. Updated the Image Position Pattient calculation for Transform>Rotate Volume, Transform>Rotate Volume Orthogonal.

4. In ROI>Theshold to ROI:  initial signal window now corresponds to the actual Min,Max voxels.

Build 462B is released.

 1. In MR-Brain Atlas workflow\Stage1:  correction so that any document could be active for proper execution.

2.  In MR-Brain Atlas workflow\Stage2: workflow :  the dialog now displays the name of the Target atlas layer.

Build 462A

 1. Fixed defect in AutoFocus registration\MC when a Target ROI has a single slice over 3D Volume.

2. In BrainMR workflow, Stage1 (AutoFocus): enforce the "Whole Brain ROI" as Target ROI.

Build 462 is released.

 1. Implemented SUV map calculation over PET volumes.

2. Major update to Dynamic Analysis> Save N-tuple file. With optional ROI and optional coordinates now. Proper handling of NAN entries.

3. FlEXR3D dialog: implemented option to output the Jacobian map of the deformation

4. Signal Difference measure in FLEXR registration: corrected numerical defect, optimized for x2 speed improvement, added the progress bar.

5. AutoFocus4D: fixed defect so that REAL images are allowed

Build 461B is released.

1. Transform>Mirror {X,Y,Z} functions:  implemented DICOM position tag modification

2. 3 Projection view: corrected behavior for the correct display.

3. Fixed defect in PR_CopyFileArr function. This also fixed defect in DICOM Open dialog Copy File functionality.

4. Create CerebrAplus atlas the includes the {WM,GM,CSF} layer.

5, Modified Brain Atlas registration workflow to permit additional custom layers in the Atlas.

 Build 461A is released.

1. Fixed defect when CDrawDoc::Display function was re-entered several times either by the same or different thread.  (fixed with critical section and enty flag).

2. PrxShell.cpp substantial rework and simplification.

Build 461

 1. Continued work on UNet3D for pancreas: replace the binary sigmoid DICE loss by the 2-class softmax DICE loss. That worked very well with binary threshold issue gone away.

2. First variant of "genetic shape crossover": augmentation technique of generating new pancreas shapes. Gained +2% DICE on NIH dataset.

3. Implemented Measure>ROI mass center distance.

4. Fixed N4 failure problem - including VS 2013 redistribution into FireVoxel now.

5. Pancreas AI work.

6. Very efficient separable convolution. Updated VolumeSmooth dialog to include "Separablem option". N3 was updated and old version eliminated.

7. Compilation with extra Security flags.

Build 460 is released.

 1. Defect corrections.

2. UNet framework for pancreas and supporting functions.

3. CerebrA brain atlas integration.

 Build 459A is released.

1. Modified layer name construction so no path is present, just the title.

2. Measure>Calculate TV:  now works for all enabled layers.

Build 459 is released.

 1. Update to the "DICOM folder -> to a folder of NII files"  GUI function.

2. Update to the "DICOM folder -> to a folder of FVX files"  GUI function.

3. Fixed a memory leak in the LoadDicomRecord function.

4.  Fixed the FireVoxel.key generation (multiple spaces problem)

5. Updated ChangeVolume Resolution  function.

6. Fixed defect in DICOM>Convert DICOM folder to NIFTI.

7. Fixed error in PFRAME VA_GetNonVoidMask( PFRAME V )

8. Experimental implementation of Genetic Algorithm (GA) for optimizing the GOMR  maps using TV-measure. Gained 2% on top of Laplacian smoothing.

9. Implemented Measure>Calculate Volume TV-2D

10. Implemented Dynamic Modelling > Output N-tuple parametric fille.

11. Removed Volume>Smooth across dynamic dimension. This was superseded by more advanced smoothing functions.

12. Fixed the DICOM folder > to FVX folder function.

13. Enabled loading NIFTI files when both Q- and S-forms are 0.

14. Workflows>Brain MRI   :  EdgeWave Express:    collapsed 3 items {Axial,Sagittal,Coronal} into a single one with the automatic orientation check.

Build 458 is released.

 1. When parsing the DICOM tree: we determine if the files were deidentified and in that case we add the PatientID to distinguish between different patient's records.

2. Corrected defect:  New layer addition and paintbrush usage now set the DocumentModified flag. So there is a warning when the User tries to close the document.

3. FLEXR3D processing dialog: added an option to save FFF (flow field file).

4. MainMenu>Tranform:  added an option to transform using FFF file.

5.  FLEXR3D\FLEXRMC added warning when SSC measure is selected to ensure the feature keypoints are enabled.

6.  Added UI Function>Test :  Combine Probability Maps to Atlas.

7.   Added UI Function>Test :  Sharpen template using Atlas

8. FLEXR cross-correlation similarity measure:  on large appertures (~16vox) obtained a 20% speed up by re-arranging the memory access during parallel execution.

9.  FLEXR SSC measure calculation : removed a major memory leak.

10. Further optimization of Crosscorrelation measure (FLEXR):  using the x86 superscalar instructions and 32-bit floating precision, achieve 32 threads X 16 superscalar operations = x512  parallelization.

11. Removed NGF (Normalize Gradient Field) similarity measure from FLEXR3D\FLEXRMC dialog options.

12. Enable the SSC similarity measure in FLEXR-MC dialog box.

13. Model 17 (IVIM segmented fit):  substantial update with improved parameter ranges etc.

14. Model 18 (IVIM biexp fit): provided update for the ranges of fitted parameters.

15. Parametric modelling dialog: when model changes - the Output parameters selection gets all unchecked to avoid confusion.

16. Corrected behavior when the new layer is added and it has diferent spatial attributes.  Now it ensures that everything matches to the base layer (resolution, slice position, orientation, etc).

17. Merged PWR.DLL and VolumeAnalyze.dll (VolumeAnalyze is removed from distribution now). This is done for linkage efficiency and removing redundancies.

Build 457 is released.

 1. Open DICOM folder:  fixed crash when the folder is empty. Provided diagnostic.

2. Fixed crash when multi-frame file is invalid. Provided diagnostic.

3. Corrected defect:  when the ROI or other layer with different resolution from base is added, now ALL spatial information is properly copied to the new layer.

4. Fixed hard to find defect:  when function FindLayerContainingName was called, the whole name of the layer including PATH was checked. Corrected: only the name title is checked, because the path contained the searched name (like Atlas)

5. Fixed defect when loading zip-compressed headers embedded in FVX files.

Build 456 is released.

0. DICOM load, STUDY construction was corrected.

 1. Defect fixed: Parametric map calculation is skipped for a voxel that has a VOIDVOX at some point.

2.  Defect fixed: exclude VOIDVOX from GOMR calculation

 Build 455A is released.

1.  Model #25 (T2-biexponential fit) is corrected to display a single curve fit correctly.

2. ABT is added for this model

 Build 455 is released.

1. Seamless integration of Multi-frame DICOM support. MF-file is automatically split into a single frame files in the temporary folder and the DICOM tree works on single-frame files.

 Build 454A is released.

1. Corrections for optional loading of FvxANN.dll

Build 454 is released.

 

 1. FLEXR 3D\MC : introduced the Regularization 32/64-bit precision option.

2. Fixed defect in optional loading of FvxANN.dll

Build 453 is released.

1. FLEXR3D:  Implemented the SSC (Self Similarity Context) registration measure.

2. Performed corrections in "Normalize by ROI" dialog box.

Build 452 is released

 1. Internal coding: Parallel Batch unified calculation

2. Model #17:  allowed volumes with two  large b-values for calculation (before it was 3).

3. Cylinder Paintbrush option.

Build 451 is released.

 1. Defect: corrected MST (minimum spanning tree) function in coordinate calculation VA_CoordFromOffs.

2. MST function speed optimization.

3. Fixed defect:   AVX512 instruction detection was always returning TRUE.

4. Parallel Batch functions (x4) consolidation.

Build 450 is released.

 1. DICOM Smoothing batch tool: performed correction for site#3 by folding STUDY UID.

2. Temporal Shape Means smoothing - implemented 2D option for a major acceleration.

3. Internal : Add Layer using Header Volume: fixed the crash defect when there was a mixture of 3D and 4D layers.

4. Neck Multimodality workflow: Updated the parameters for CT->GRASP FLEXR registration.

Build 449A is released.

 1. Dynamic Model #10: rebuilt from scratch to use modern framework.

2. Duplicate Model 11 is removed from the interface.

Build 449 is released.

 1. >ROI>Threshold To ROI  GUI function: parallelized and added a progress bar. It was slow on really big REAL images (300MB+).

2. Increased the REAL Image compression threshold: this is so the images are only compressed when it is worth more. This really speeds up the viewing.

3. Corrected the ParalleBatch {Length,NumberOfBatches} calculation function.

4. FLEXR3D\FLEXRMC dialogs : added an option to Inflate target ROI (similar to AutoFocus3D)

5. FELXR: Minimum Spanning Tree : added the progress bar.

6. Cross Correlation function : upgraded from AVX2 to AVX512

7.  Implemented Hip registration workflow.

8. Fixed defect: Layer Control Dialog: SaveAll (fixed the orientation issue when saving to NIFTI volumes)

9. Fixed defects in API:VolSetSlice function.

10. Fixed defects in Temporal Shape Means function

11. DICOM Folders : Conventional Smoothing to Target DICOM Folder.

12. DICOM Folders : TSM Smoothing to Target DICOM Folder.

13. Remove Multipass from FLEXR dialogs.

Build 448A is released.

 1. GUI: Implemented the Volume>"Multilayer Document PCA" function.

2. "Batch Fix DICOM tags...": provided a better diagnostics message.

Build 448 is released.

 1. FLEXR: Introduce vicinity rotation invariance for similarity measures. Applied it to the X-correlation measure.

2. Brain Atlas GUI: implemented menu items for Stage1 and 2SW-Stage2 processing.

3. FLEXR: Removed OptiMap measure from Menu choices.

4. Re-implemented important IsRoiEmpty function so it works very fast and without decompression.

5. Removed all the items related to Ultra Sound processing.

6. Incorporated the IsRoiSliceEmpty fast check into zooming pipeline. It was x6 time faster for Mindboggle atlas with 70 ROIs.  Also incroporated into FilmView for a similar speedup.

7. Regular Grid keypoint generation:  corrected the adjacency checking to comply with keypoint positision in voxel corner (not vertex).

8. Complete rework of Roi Surface keypoints. Vertice correction and speed up. 

9. Autofocus3D:CalculateMeasure: removed sub-code for SignalDifference using RL-encoding.

10. Corrected FLEXR ROI padding calculation to include all measures.

11. Removed FLEXR legacy algorithm

12. Corrected crash defect : in Affine Reslicing when the resulting volume exceeds 4GB.

13. FLEXR\Similarity: adjusted vicinity calculation in case single slice (2D) image.

Build 447 is released.

 1. Re-implemented the dense Flow field generation, so it works correctly when the initial transform is general affine (as opposed to scale+translation)

2. FLEXR : implemented the VOID voxel concept in Target and Source images. Modified all registration metrics to work properly with VOID voxels. This is especially important for Atlas representation.

3. Atlas based registration : added the workflow item.  Atlas is automatically split into the regions that appear as the individual layers.

4. Made corrections in Neck Multimodality workflow - Step 15.

Build 446B is released.

 1.  Neck Workflow :  DWI Body segmentation automatically advances to starting timepoint.

2. FLEXR:  Local Mutual Info - progress bar added and memory usage substantially decreased.

3. FLEXR : prevent running when no keypoints were specified.

Build 446A is released.

1. Corrections FLEXR when registering 4D volume to 3D.

2. FLEXR-MC dialog simplifications.

Build 446 is released.

 1. Minimum Spanning Tree algorithm update with keypoint re-arrangement in the order of the Tree width-first traverse.

2. FLEXR: developed a multipass version of this algorithm running on 1/3 of RAM.  Multipass allows to start minimum spanning tree from several distant positions to compensate for tree approximation.

3. NW flow field generation:  provided an AVX256 implementation for x2 speedup.

4. NW flow Sparse-to-Dense:  implemented algorithm for filtering out remote keypoints for speedup. This was based on evaluating Y-Z exponents and introdducing some minor artefacts.

5. Volume-to-concentration conversion: fixed defect when VOID voxels were treated as regular ones calculating an infinite concentration as a result.

6. Completely re-engineered sparse-to-dense flow field generation for upto x20 speed up (on CT Lung 5 mm grid)

7. Workflow>Breaset MR BPE : implemented Whole Breast Segmentation function

8. File>DICOM>Dicom Tree to Folders   : fixed defect when composite SERIES were not able to convert to folder.

9. VA_VolSegHist:  fixed defect. This function was returning thresholds measured in Histogram bins. Corrected to signal.

10.  Workflow>BPE breast :  added a one-click function for FGT segmentation.

11.  Workflow>BPE breast: added function for 3D motion correction.

12, MainMenu>Dynamic Analysis:   enabled work without supplying the T1-map so only T1W conversion is enabled.

13. Simplified the FLEXR 3D/MC menues.

Build 445 is released.

1. VA_RAW_VolSaveFile function: optimized when CurrTinx!=1 only the required timepoint is decompressed.

2. New GUI function: Convert folder of FVX files into a target folder with separate subfolder for each FVX file. For each FVX subfolder save all layers to NII files.

3. Provided FLEXR RAM estimation function and comparison to the system resources.

4. Updated MR Lung segmentation algorithm

Build 444 is released.

 1. FLEXR fixed defect so the registered volumes have the same Image Position\Orientation as the Target volume.

2. Updated the Machine GUID scrambling algorithm.

3. Neck multimodality workflow:  added the DWI Body Segmentation and DWI->GRASP registration.

4. Improved the FLEXR masking algorithm, both Smask and Tmask.

5. FLEXR perform corrections is Target->Source output option.

6. Fixed defect in bool VA_VolOverRoi_AvgMinMax, that was affecting the Optimal Intensity Window.

7. FLEXR3D works now when the Source volume is 4D, so it would reslice all timepoints and produce a 4D layer.

8. Fixed defect in DisplayVoxelInfo (status line), so the VOID voxel location show the dynamic index too.

9. Provided a first version of Neck Multimodality 15 step workflow combining PET, CT, GRASp,DWI.

10. Compare documents\compare volumes : provided the comparison function which works on compressed image data, so there is no need to decompress for the comparison.

11. Huffman compression of DICOM headers: upgraded to 64-bit and corrected when the longest H-code exceeded 24-bit.

12. Updated the Machine GUID scrambling scheme.

Build 443 is released.

 1. EdgeWave UI dialog box: fixed defect when Absolute Core SI was not accepting negative values (f.e. Real CT).

2. FLEXR3D dialog UI: added the Initial Transform option

3. FLEXR:InitialAlignment - substantial algorithm re-engineering.

4. Neck Multimodlaity Workflow: Added GUI function for the initial Ct to GRASP alignment.

5. FLEXR3D: implemented the FLEXR with Initial Transform file (vtf).

6. Expanded the FVX License key file to  include Windows Machine GUID.

7. Corrected the WC\WL setting in Volume View Filter dialog.

 Build 442 is released.

1. Developed a new tool for checking precision of motion correction "Motion Profile Diagram". This is based on Gene Kim's 2007 JMRI paper.

2. Extended the logic of loading DICOM 4D Volumes based on Series Description tag.

 Build 441 is released.

1. Volume Layer: ViewFilter dialog box (INT,REAL) : introduced new "Adaptive Window Level\Width option". It optimizes mapping to screen for every zoom. Very  useful for comparing registration results on dark timepoints such as last b-values.

2. LayerControl dialog : implemented  "Interlaced View" option {X,Y,XY} so the layers are seen in overlacing manner.

3. Volume>Split 4D volume into layers" : for 4D volumes splits each separate timepoint into a document layer. Useful for viewing motion correction results.

4. Upgraded to FVX file format v17 due to above (#1,2) changes.

Build 440 is released.

 1. Internal: upgraded VolumePad function to work with 4D volumes.

2. Implemented prototype of NLM-D denoising (when TACs are compared for each location), as opposed to perform NLM for each timepoint separately.

3. When saving volumes with Void orientation to NIFTI, display a warning and save in default orientation.

4. Implemented new denoising algoritm: Temporal Shape Means (with GUI)

5. Implemented new denoising algoritm: Spatial Temporal Shape Means (with GUI).

6. Dynamic framework can now output the Model volume for every voxel (modified GUI by adding a check to the dialog box).

7. Numpy load COMPLEX64 support was added.

8. Fixed FLEXR3D crash on single slice volumes (regular grid generation).

9. Fixed crash in Gaussian smoothing function applied to ROI.

10. BPE map and report generation: changed to average Slope (from Start-End slope). Allowed function to work on any number of timepoints.

11, Added support for additional variety of SIEMENS b-value encoding in SEQUENCE_NAME tag.

Build 439 is released.

 1. Non-local Means denoising : expanded to optionally process all timepoints.

2. Implemented a GUI dialog for loading {2,3,4} dimensional matrices as volumes (File>Open RAW data).

3. Numpy format support under the File>Open RAW data

Build 438A is released.

1. FLEXR:Regularization :  speedup parallelizing the  Cost1,Cost2 updates.

2. DICOM load timings: updated the logic so the the timing DICOM tags are skipped

if they are present but have empty value. 

3. Build test unit for the FLEXR with Jacobian calculation

Build 438 is released.

 1. Fixed defect in AutoFocus3D registration : new registered layer now have orientation of the Target layer.

2. Developed first prototype of Multi-Protocol brain registration workflow (MRI 'Change Map"display project)

3. Developed Rigid and Elastic workflow for the MPRAGE longitudal brain change.

4. Developed Rigid workflow for the ADNI phantom longitudal comparison.

5. Upgraded Jacobian map calculation 

    a) To use central-difference calculations

    b) To be able to work when Source and Target volumes have different resolution.

6. Implemented analytical calculation of the Jacobian maps for NW transform (during the elastic registration FLEXR).

7. ViewTac dialog : fixed defect when the entire curve has VOIDVOX values.

8. Internal:  extended VA_VolGetBox\GetSlice functions to accept T=-1 (all timepoints)

9. Workflow: Segmentation\MotionCorrection item now outputs {Jacobian,DispY,DispDistance} mea1sures of the field.

10 NW transofrm was simplified by removing the cut-off conditions on the remote voxels.

11. Streamline code and optimized speed of EDTF calculation (part of FLEXR algorithm : regularization).

12. Optimized ROI Inflate\Deflate function (x4 speed up). This is used in UI and FLEXR.

13. FLEXR:  x1.5 speed up of the X-correlation similarity measure values calculations.

14.  Parallelized "IsInfiniteArray" function for testing infinite double values.  Part of FLEXR:Regularization.   x8 speed up on very large arrays (2Bill elements).

 Build 437C is released.

1. Fixed defect in Radiomics2D header output.

Build 437B is released.

1. NIFTI load\orientation: fixed defect in logic when the non-orthogonality of orientation exceeds the threshold.

Build 437A is released.

 1. Modified Radiomics "First order features" to include NumEffVoxels : number of voxels that are present in the current specified range of the Histogram

2. When loading NIFTI file, increased the orientation "orthogonality tolerance" to 1e-4

Build 437 is released.

 1. Fixed major defect in Dynamic framework: for CT dynamic volumes, concentration conversion of Input Function was not performed.

2. Implemented GoMR for Model57 (Ktrans).

3. GO and GOMR algorithm improvements.

4. Flatline threshold mechanism implemented.

5. Fixed defect in batch module BM3 reporting the number of ROI working voxels.

Build 436 is released.

 1. MainMenu>Measure>All Layers Irregularrity2D :   modified to process all Documents and all Layers.

2. MainMenu>Measure : All Real Volume : Calculate mean over all ROIs:  modified to process all Documents.

3. Implemented the ABT unit test for BM3 module.

4. Extended BM1 tool to work on multilayer folders of NIFTI images and ROIs.

Build 435A is released.

1. NIFTI save: corrected processing when effective number of bits=8

2.  NIFTI save: corrected orientation defect when saving 1-slice 4D volumes.

3. Radiomics dialog:  GLDM feature checkbox was not working.

Build 435 is released.

 1. Fixed defect in BM3 module (crash or "no valid voxels" message)

2. View Projection dialog diasables the slab controls when slab type = NORMAL.

3. Detection of Multiframe DICOM files and suggesting to the User how to process them.

4. Parallelized detection of DICOM files to allow browsing through very large collections of files.

5. Implemented function to measure the cross-correlation (ZNCC) between 2 layers with the optional ROI.

 Build 434 is release.

1. Implemented GOMR (Global Optimization Map Regularization) technology for Models 18 (IVIM) and Model 52 (Gamma variate fit).

 Build 433B is released.

1. General dynamic framework corrections for GOMR integration.

 Build 433A is released.

1. Implemented the feature so computer does not go to sleep while in FireVoxel Work process (=progress bar is running).

Build 433 is released.

1. Integrated the DCMJP2K library from (DICOM OFFIS) for the Jpeg2000 support.

2. Fixed saving DICOM header for the extra large header (increased the buffer from

3. Fixed crash after multiple pressing of {NewROI3D,NewROI4D,Duplicate} in layer dialog box. This was due to intermingling of numerous Work and UI threads.

            Publications using FireVoxel:  May 2021 - August 2023

1. Quant Imaging Med Surg. 2023 Jul 1; 13(7): 4268–4283.

Published online 2023 May 9. doi: 10.21037/qims-22-1084

PMCID: PMC10347354

PMID: 37456319

Improvements of the Tada formula in estimating the intracerebral hemorrhage volume based on computed tomography

Zhuang Sha,# 1 , 2 , # Xinjie Zhang,# 1 , 2 , # Zhanying Li,# 1 , 2 , 3 , # 

Jiancheng Feng, 1 , 2 Wei Quan, 1 , 2 Shiying Dong, 1 , 2 Mingqi Liu, 1 , 2 Weiwei Jiang

2. Brain-Penetrable Bi-specific Antibody Radioligands for in vivo PET Imaging of Tauopathy

Andrew Kelleher, Brandon Richardson, VINAY KUMAR BANKA, Alex Kazior, Cathy Tan, Sabrina Chan, Rumaish Khastgir, Hao Hu, Zakia Youss, 

Mishkit Orin, Yan Lin, Dag Sehlin, Greta Hultqvist, Einar Sigurdsson, Stina Syvanen and Yu-Shin Ding

Journal of Nuclear Medicine June 2023, 64 (supplement 1) P271;

3. Histograms of Computed Tomography Values in Differential Diagnosis of Benign and Malignant Osteogenic Lesions

Heliyon

21 Pages Posted: 10 Aug 2023 Publication Status: Preprint

Ruiqing Wang

Qingdao University Ruizhi Zhou Qingdao University Shiqing Sun Qingdao University Zhitao YangQingdao University Haisong Chen

4. Magnetic Resonance

Published: 17 June 2021

Volumetric ADC histogram analysis for preoperative evaluation of LVSI status in stage I endometrioid adenocarcinoma

Xiaoliang Ma, Xiaojun Ren, Minhua Shen, Fenghua Ma, Xiaojun Chen, Guofu Zhang & Jinwei Qiang 

European Radiology volume 32, pages460–469 (2022)Cite this article

5. European Journal of Radiology

Volume 140, July 2021, 109745

European Journal of Radiology

The role of volumetric ADC histogram analysis in preoperatively evaluating the tumour subtype and grade of endometrial cancer

Author links open overlay panelXiaoliang Ma a, Minhua Shen b, Yimeng He b, Fenghua Ma b, Jia Liu b, Guofu Zhang b, Jinwei Qiang a

https://doi.org/10.1016/j.ejrad.2021.109745

6. Magnetic Resonance Imaging

Volume 100, July 2023, Pages 93-101

Magnetic Resonance Imaging

Characterization of motion dependent magnetic field inhomogeneity for DWI in the kidneys

Nima Gilani a, Artem Mikheev a, Inge M. Brinkmann b, Dibash Basukala a, Thomas Benkert c, Malika Kumbella a, James S. Babb a, Hersh Chandarana a, Eric E. Sigmund a

https://doi.org/10.1016/j.mri.2023.03.008

7. MDPI

Evaluation of Whole-Tumor Texture Analysis Based on MRI Diffusion Kurtosis and Biparametric VI-RADS Model for Staging and Grading Bladder Cancer

by Xiaoyan Meng 1,Shichao Li 1,Kangwen He 1,Henglong Hu 2ORCID,Cui Feng 1ORCID,Zhen Li 1ORCID andYanchun Wang 1,*ORCID

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China

Author to whom correspondence should be addressed.

Bioengineering 2023, 10(7), 745; https://doi.org/10.3390/bioengineering10070745

Received: 18 May 2023 / Revised: 16 June 2023 / Accepted: 18 June 2023 / Published: 21 June 2023

8. Future Oncology. Vol 19

More accurate prediction of treatment response than mean apparent diffusion coefficient value in multiple myeloma using whole body MRI histogram analysis

Qingyan Qi‡, Huazheng Dong‡ , Xiaodong Ji‡, Kemin Zhang, Dehui Zou, Mu Hao, Shuhui Deng, Weiwei Sui, Zhiyi Song, Zhuo Yu, Zhiwei Shen, Wenyang Huang & Shuang Xia 

Published Online:30 Jun 2023https://doi.org/10.2217/fon-2023-0205

9. Front. Oncol., 28 October 2022

Sec. Cancer Imaging and Image-directed Interventions

Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.957737

Study on the changes of CT texture parameters before and after HCC treatment in the efficacy evaluation and survival predication of patients with HCC

Wei Zhou1 Yinzhang Lv1* Xuemei Hu1 Yan Luo1 Jiali Li1 Haidan Zhu1 Yucheng Hai1,2

1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2Department of Radiology, Lanzhou University Second Hospital, Lanzhou, China

10. Magnetic Resonance Imaging

Volume 85, January 2022, Pages 262-270

Magnetic Resonance Imaging

Correlation between molecular prognostic factors and magnetic resonance imaging intravoxel incoherent motion histogram parameters in breast cancer

Wen Feng a b, Ya Gao b, Xing-Ru Lu b, Yong-Sheng Xu b, Zhuan-Zhuan Guo c, Jun-Qiang Lei b

https://doi.org/10.1016/j.mri.2021.10.027

11.  Journal of Molecular Imaging  > 2022  >  45(4): 480-485

Citation: WANG Hongrui, LI Jinling, ZHANG Qiang, ZHANG Keqin, ZHANG Hu. MRI apparent diffusion coefficient histogram and serum CA125 help to 

evaluate the histopathological characteristics of endometrial adenocarcinoma[J]. Journal of Molecular Imaging, 2022, 45(4): 480-485. doi: 10.12122/j.issn.1674-4500.2022.04.04 shu

MRI apparent diffusion coefficient histogram and serum CA125 help to evaluate the histopathological characteristics of endometrial adenocarcinoma

doi: 10.12122/j.issn.1674-4500.2022.04.04

12.  Kidney International Reports

Volume 8, Issue 5, May 2023, Pages 1057-1067

Kidney International Reports

Clinical Research

Quantitative Blood Oxygenation Level Dependent Magnetic Resonance Imaging for Estimating Intra-renal Oxygen Availability Demonstrates Kidneys Are Hypoxemic in Human CKD

Pottumarthi V. Prasad 1 3, Lu-Ping Li 1 3, Bradley Hack 1, Nondas Leloudas 1, Stuart M. Sprague 2 3

https://doi.org/10.1016/j.ekir.2023.02.1092

13.  

Neurosurgical Review 

Published: 02 September 2023

Whole-tumor histogram analysis of multi-parametric MRI for differentiating brain metastases histological subtypes in lung cancers: relationship with the Ki-67 proliferation index

Bin Zhang, Fengyu Zhou, Qing Zhou, Caiqiang Xue, Xiaoai Ke, Peng Zhang, Tao Han, Liangna Deng, Mengyuan Jing & Junlin Zhou 

Neurosurgical Review volume 46, Article number: 218 (2023) Cite this article

14. Chinese Journal of CT and MRI

Relationship b e t w e e n I m a g e 

Heterogeneity of Multiple Glioma and 

Tumor Biological Behavior Based on 

Multimodal MRI Combined with Histogram

GUAN Xiu-hong* .

Image Center of Dezhou Second People's Hospital, Dezhou 253000, Shandong Province, China

15. ALZHEIMER'S IMAGING CONSORTIUM

In vivo imaging of LC-NE Integrity: Mechanism for racial/ethnic disparity in preclinical AD

Yu-Shin Ding, Jiacheng Wang, Henry Rusinek, James Babb

First published: 31 December 2021 https://doi.org/10.1002/alz.050955

16. Cancer Imaging

Published: 12 June 2023

Ultra-high b-Value DWI in predicting progression risk of locally advanced rectal cancer: a comparative study with routine DWI

Guangwen Zhang, Ziliang Xu, Jianyong Zheng, Mian Wang, Jialiang Ren, Xiaocheng Wei, Yi huan & Jinsong Zhang 

Cancer Imaging volume 23, Article number: 59 (2023) Cite this article

17. NeuroImage: Clinical

Volume 37, 2023, 103353

NeuroImage: Clinical

MRI histogram analysis of tumor-infiltrating CD8+ T cell levels in patients with glioblastoma

Caiqiang Xue a b c d 1, Qing Zhou a b c d 1, Peng Zhang e, Bin Zhang a b c d, Qiu Sun a b c d, Shenglin Li a b c d, Juan Deng a b c d, Xianwang Liu a b c d, Junlin Zhou a b c d

https://doi.org/10.1016/j.nicl.2023.103353

18. Academic Radiology

Volume 28, Supplement 1, November 2021, Pages S184-S191

Academic Radiology

Preliminary Study on Predicting Pathological Staging and Immunohistochemical Markers of Rectal Cancer Based on ADC Histogram Analysis

Author links open overlay panelKeke Zhang Master of Medicine a b c d, You Zheng Master of Medicine a b c d, Hongliang Huang Master of Medicine a b c d, Junqiang Lei PhD b c d

https://doi.org/10.1016/j.acra.2021.02.004

19. Cardiac Phase and Flow Compensation Effects on REnal Flow and Microstructure AnisotroPy MRI in Healthy Human Kidney

Eric E. Sigmund PhD, Artem Mikheev PhD, Inge M. Brinkmann PhD, Nima Gilani PhD, James S. Babb PhD, Dibash Basukala PhD, Thomas Benkert PhD, Jelle Veraart PhD, Hersh Chandarana MD

First published: 18 November 2022 https://doi.org/10.1002/jmri.28517Citations: 2

Contract grant sponsor: NIH (R01CA245671).

20. Differences in apparent diffusion coefficient histogram analysis according to EGFR mutation status in brain metastasis due to lung adenocarcinoma

Article type: Research Article

Authors: Bilgin, Ezel Yaltırıka; * | Ünal, Özkana | Göç, Muhammed Fatiha | Bahşi, Tahab

Affiliations: [a] Department of Radiology, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey | [b] Department of Medical Genetics, Dr. Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital, Ankara, Turkey

DOI: 10.3233/XST-230084

Journal: Journal of X-Ray Science and Technology, vol. Pre-press, no. Pre-press, pp. 1-11, 2023

Received 19 April 2023 | 01 June 2023 | Accepted 19 June 2023 | Published: 06 July 2023

21. Alzheimer's & Dementia

BIOMARKERS

MRI longitudinal and cross-sectional monitoring of amyloid pathology in non-human primates

Thomas S. Genovese, Dina Ramadane, Charles Kingsley, Pramod N. Nehete, Akash G. Patel, Jonathan Leung, Miroslav Tibensky, Henry Rusinek, Stanton B. Gray … See all authors 

First published: 01 February 2022 https://doi.org/10.1002/alz.055017

22. European Journal of Radiology

Volume 157, December 2022, 110587

European Journal of Radiology

Quantitative multiparametric MRI as a promising tool for the assessment of early response to neoadjuvant chemotherapy in bladder cancer

Xiao Yang a 1, Baorui Yuan a c 1, Yudong Zhang b 1, Juntao Zhuang a 1, Lingkai Cai a, Qikai Wu a, Qiang Cao a, Pengchao Li a, Qiang Lu a, Xueying Sun b

https://doi.org/10.1016/j.ejrad.2022.110587

23. The Neuroradiology Journal

Research article

First published online October 5, 2021

Differentiation of brain metastases originating from lung and breast cancers using apparent diffusion coefficient histogram analysis and the relation of histogram parameters with Ki-67

Mustafa Bozdağ https://orcid.org/0000-0002-0741-587X bozdagmustafa.84@gmail.com, Ali Er, and Sümeyye EkmekçiView all authors and affiliations

Volume 35, Issue 3

https://doi.org/10.1177/19714009211049082

24. Frontiers in Oncology

ORIGINAL RESEARCH article

Front. Oncol., 19 June 2023

Sec. Gynecological Oncology

Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1206659

Whole-tumor histogram analysis of apparent diffusion coefficients for predicting lymphovascular space invasion in stage IB-IIA cervical cancer

Jin-mei Cheng1 Wei-xiao Luo1 Bang-guo Tan2 Jian Pan3 Hai-ying Zhou1* Tian-wu Chen1*

1Sichuan Key Laboratory of Medical Imaging, and Department of Radiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan, China

2Department of Radiology, Panzhihua Central Hospital, Panzhihua, Sichuan, China

3Department of General Practice, Taiping Town Central Health Center, Leshan, Sichuan, China

25. ORIGINAL RESEARCH article

Front. Oncol., 25 January 2023

Sec. Cancer Imaging and Image-directed Interventions

Volume 13 - 2023 | https://doi.org/10.3389/fonc.2023.1076400

Incremental prognostic value of ADC histogram analysis in patients with high-risk prostate cancer receiving adjuvant hormonal therapy after radical prostatectomy

Kangwen He1† Yucong Zhang2† Shichao Li1 Guanjie Yuan1 Ping Liang1 Qingpeng Zhang3 Qingguo Xie4 Peng Xiao4 Heng Li5* Xiaoyan Meng1* Zhen Li1

1Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

2Department of Geriatrics, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

3School of Data Science, City University of Hong Kong, Hong Kong, Hong Kong SAR, China

4College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China

5Department of Urology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

26. Glioblastoma Recurrence Versus Radiotherapy Injury

Combined Model of Diffusion Kurtosis Imaging and 11C-MET Using PET/MRI May Increase Accuracy of Differentiation

Dang, Haodan MD∗; Zhang, Jinming MD∗; Wang, Ruimin MD∗; Liu, Jiajin MS∗; Fu, Huaping MS∗; Lin, Mu PhD†; Xu, Baixuan MD∗

Clinical Nuclear Medicine 47(6):p e428-e436, June 2022. | DOI: 10.1097/RLU.0000000000004167

27. BMC Cancer

Published: 25 August 2022

The value of diffusion kurtosis imaging and intravoxel incoherent motion quantitative parameters in predicting synchronous distant metastasis of rectal cancer

Xue Ding, Danqi Sun, Qiuchen Guo, Yeting Li, Hao Chen, Xiaoxiao Dai, Guohua Fan, Yongyou Wu, Guangqiang Chen & Yonggang Li 

BMC Cancer volume 22, Article number: 920 (2022) Cite this article

28. Clinical Radiology

Volume 78, Issue 7, July 2023, Pages 532-539

Differentiation of giant cell tumours of bone, primary aneurysmal bone cysts, and aneurysmal bone cysts secondary to giant cell tumour of bone: using whole-tumour CT texture analysis parameters as quantitative biomarkers

Author links open overlay panelJ.-Y. Wang a, D. Sun a, C.-Y. Liu a, B.-W. Hou a, Y.-T. Li a, S. Hu a, Y. Zhang a, J.N. Morelli b, X.-M. Li a

Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China

Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Received 12 October 2022, Revised 15 February 2023, Accepted 6 March 2023, Available online 23 March 2023, Version of Record 29 May 2023.

29.  J Hypertens. 2023 Jan; 41(1): 35–43.

Published online 2022 Oct 4. doi: 10.1097/HJH.0000000000003292

PMCID: PMC9794123

PMID: 36204999

Quadratic relationship between systolic blood pressure and white matter lesions in individuals with hypertension

Christopher Woldstad, a Henry Rusinek, b Elizabeth Sweeney, c Tracy Butler, a Yi Li, a Emily Tanzi, a Christopher Mardy, a Patrick Harvey, a Mony J. de Leon, a and Lidia Glodzik

30.  Placenta

Volume 135, April 2023, Pages 16-24

Placenta

Placental perfusion using intravoxel incoherent motion MRI combined with Doppler findings in differentiating between very low birth weight infants and small for gestational age infants

Jing Deng a 1, Aining Zhang a 1, Meng Zhao a, Xin Zhou b, Xihu Mu a, Feifei Qu c, Jiacheng Song a, Ting Chen a

https://doi.org/10.1016/j.placenta.2023.02.005

31. Korean J Radiol. 2022 Jun; 23(6): 664–673.

Published online 2022 Apr 26. doi: 10.3348/kjr.2021.0627

PMCID: PMC9174502

PMID: 35555881

T2 Mapping with and without Fat-Suppression to Predict Treatment Response to Intravenous Glucocorticoid Therapy for Thyroid-Associated Ophthalmopathy

Linhan Zhai,1,2 Qiuxia Wang,1 Ping Liu,3 Ban Luo,4 Gang Yuan,5 and Jing Zhangcorresponding author1

32. Magnetic Resonance

Published: 27 May 2021

Dynamic contrast-enhanced MRI perfusion quantification in hepatocellular carcinoma: comparison of gadoxetate disodium and gadobenate dimeglumine

Daniel Stocker, Stefanie Hectors, Octavia Bane, Naik Vietti-Violi, Daniela Said, Paul Kennedy, Jordan Cuevas, Guilherme M. Cunha, Claude B. Sirlin, Kathryn J. Fowler, Sara Lewis & Bachir Taouli 

European Radiology volume 31, pages9306–9315 (2021)

33. nature  scientific reports 

Published: 03 August 2022

Positron Emission Tomography reveals age-associated hypothalamic microglial activation in women

Tracy Butler, Lidia Glodzik, Xiuyuan Hugh Wang, Ke Xi, Yi Li, Hong Pan, Liangdong Zhou, Gloria Chia-Yi Chiang, Simon Morim, Nimmi Wickramasuriya, Emily Tanzi, Thomas Maloney, Patrick Harvey, Xiangling Mao, Qolamreza Ray Razlighi, Henry Rusinek, Dikoma C. Shungu, Mony de Leon, Craig S. Atwood & P. David Mozley 

Scientific Reports volume 12, Article number: 13351 (2022) Cite this article

34. Ann Transl Med. 2021 Nov; 9(21): 1614.

doi: 10.21037/atm-21-2299

PMCID: PMC8640904

PMID: 34926658

Assessment of renal function using magnetic resonance quantitative histogram analysis based on spatial labeling with multiple inversion pulses

Ping Liang, 1 Shichao Li, 1 Chuou Xu, 1 Jiali Li, 1 Fangqin Tan, 1 Daoyu Hu, 1 Ihab Kamel, 2 and Zhen Licorresponding author 1

35. Quant Imaging Med Surg. 2021 Jun; 11(6): 2453–2464.

doi: 10.21037/qims-20-578

PMCID: PMC8107337

PMID: 34079715

Utility of noncontrast MRI in the detection and risk grading of gastrointestinal stromal tumor: a comparison with contrast-enhanced CT

Ziling Zhou,1,^ Jingyu Lu,1,^ John N. Morelli,2,^ Daoyu Hu,1,^ Zhen Li,1,^ Peng Xiao,3,^ Xuemei Hu,1,^ and Yaqi Shencorresponding author1,^

36. Front. Oncol., 13 October 2022

Sec. Cancer Imaging and Image-directed Interventions

Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.985735

Role of diffusion-weighted MRI in differentiation between benign and malignant anterior mediastinal masses

Tran Thi Mai Thuy1,2 Nguyen Truong Hoang Trang1,2 Tran Thanh Vy3,4 Vo Tan Duc1,2 Nguyen Hoang Nam1,2 Phan Cong Chien1 Le Huu Hanh Nhi5† Le Huu Nhat Minh6,7,8*†

37. 3D Printing for the Radiologist

2022, Pages 31-43

3D Printing for the Radiologist

Chapter 3 - Image Segmentation and Nonuniformity Correction Methods

Jingyun Chen PhD, Louisa Bokacheva PhD, Henry Rusinek PhD

38. Yuan, G., Qu, W., Li, S. et al. 

Noninvasive assessment of renal function and fibrosis in CKD patients using histogram analysis based on diffusion kurtosis imaging. 

Jpn J Radiol 41, 180–193 (2023). https://doi.org/10.1007/s11604-022-01346-2

39. Gynecologic Oncology

Volume 165, Issue 3, June 2022, Pages 594-602

Gynecologic Oncology

Volumetric apparent diffusion coefficient (ADC) histogram metrics as imaging biomarkers for pretreatment predicting response 

to fertility-sparing treatment in patients with endometrial cancer

Xiaoliang Ma a 1, Xiaojun Ren b 1, Fenghua Ma c, Shulei Cai c, Chengcheng Ning b, Jia Liu c, Xiaojun Chen b, Guofu Zhang c, Jinwei Qiang a

https://doi.org/10.1016/j.ygyno.2022.04.008

40. Front. Pain Res., 11 May 2022

Sec. Abdominal and Pelvic Pain

Volume 3 - 2022 | https://doi.org/10.3389/fpain.2022.720141

This article is part of the Research Topic

Emerging Trends in Abdominal And Pelvic Pain

Menstrual Cycle Variation in MRI-Based Quantification of Intraluminal Gas in Women With and Without Dysmenorrhea

Hyeyoung Oh1 Eli D. Ehrenpreis2 Frank F. Tu1,3 Katlyn E. Dillane1 Ellen F. Garrison1 Nondas Leloudas4 Pottumarthi V. Prasad4,5 Kevin M. Hellman1,3*

41. Radiomics-Based Image Phenotyping of Kidney Apparent Diffusion Coefficient Maps: Preliminary Feasibility & Efficacy

by Lu-Ping Li 1,*,†,Alexander S. Leidner 2,†,Emily Wilt 1,Artem Mikheev 3,Henry Rusinek 3,Stuart M. Sprague 4,Orly F. Kohn 5,‡,Anand Srivastava 2,§ORCID andPottumarthi V. Prasad 1,§ORCID

J. Clin. Med. 2022, 11(7), 1972; https://doi.org/10.3390/jcm11071972

Received: 7 March 2022 / Revised: 25 March 2022 / Accepted: 29 March 2022 / Published: 1 April 2022

42. Pol J Radiol. 2021; 86: e298–e308.

Published online 2021 May 19. doi: 10.5114/pjr.2021.106427

PMCID: PMC8186307

PMID: 34136048

3D quantitative analysis of diffusion-weighted imaging for predicting the malignant potential of intraductal papillary mucinous neoplasms of the pancreas

Takao Igarashi,A,B,C,D,E,F Megumi Shiraishi,B Ken Watanabe,B Kazuyoshi Ohki,D Shinsuke Takenaga,E Hirokazu Ashida,E and Hiroya OjiriE

43. Choroid Plexus Calcification Correlates with Cortical Microglial Activation in Humans: A Multimodal PET, CT, MRI Study

T. Butler, X.H. Wang, G.C. Chiang, Y. Li, L. Zhou, K. Xi, N. Wickramasuriya, E. Tanzi, E. Spector, I. Ozsahin, X. Mao, Q.R. Razlighi, E.K. Fung, J.P. Dyke, T. Maloney, A. Gupta, A. Raj, D.C. Shungu, P.D. Mozley, H. Rusinek and L. Glodzik

American Journal of Neuroradiology June 2023, DOI: https://doi.org/10.3174/ajnr.A7903

44. MDPI:Cancers

 Differences in the MRI Signature and ADC Values of Diffuse Midline Gliomas with H3 K27M Mutation Compared to Midline Glioblastomas

by Peter Raab 1,*ORCID,Rouzbeh Banan 2,Arash Akbarian 3,Majid Esmaeilzadeh 4,

Madjid Samii

 5,Amir Samii 5,Helmut Bertalanffy 5,Ulrich Lehmann 6,Joachim K. Krauss 4ORCID,Heinrich Lanfermann 1ORCID,Christian Hartmann 6,† andRoland Brüning 7,†ORCID

Cancers 2022, 14(6), 1397; https://doi.org/10.3390/cancers14061397

Received: 31 December 2021 / Revised: 26 February 2022 / Accepted: 6 March 2022 / Published: 9 March 2022

45.

Computational and Mathematical Methods in Medicine.

Volume 2022 | Article ID 7746991 | https://doi.org/10.1155/2022/7746991

Show citation

MR Image Classification for Brain Tumor Texture Based on Pseudo-Label Learning and Optimized Feature Extraction

Qianqian Xu ,1Huachang Xu ,1Jie Liu ,1Mingxia Zhou,1Min Li,1Jinhui Xu,2and Hong Zhu

46.   European Radiology  Article

Magnetic Resonance

Published: 06 May 2023

Value of multiparametric magnetic resonance imaging for evaluating chronic kidney disease and renal fibrosis

Chenchen Hua, Lu Qiu, Leting Zhou, Yi Zhuang, Ting Cai, Bin Xu, Shaowei Hao, Xiangming Fang, Liang Wang & Haoxiang Jiang 

European Radiology volume 33, pages5211–5221 (2023)Cite this article

47. Schizophrenia Research

Volume 247, September 2022, Pages 101-115

Schizophrenia Research

An integrative study of the microbiome gut-brain-axis and hippocampal inflammation in psychosis: Persistent effects from mode of birth

Peter Joe a, Jose C. Clemente b, Enrica Piras b, David S. Wallach b, Jessica Robinson-Papp c, Emeka Boka a, Brooke Remsen a b, Mharisi Bonner a, David Kimhy a, Deborah Goetz a, Kevin Hoffman d, Jakleen Lee b, Eugene Ruby e, Sarah Fendrich a f, Oded Gonen g, Dolores Malaspina a

https://doi.org/10.1016/j.schres.2021.09.019

48. Diagnostic and Interventional Imaging

Volume 102, Issue 5, May 2021, Pages 287-295

Diagnostic and Interventional Imaging

Neuroradiology

Texture analysis of apparent diffusion coefficient (ADC) map for glioma grading: Analysis of whole tumoral and peri-tumoral tissue

Radwa K. Soliman a, Abdelhakeem A. Essa b, Ahmed A.S. Elhakeem c, Sara A. Gamal a, Mohamed M.A. Zaitoun d

49. Ming Li, Xiaodan Xu, Kaijian Xia, Heng Jiang, Jianlong Jiang, Jinbing Sun, Zhihua Lu, 

"Comparison of Diagnostic Performance between Perfusion-Related Intravoxel Incoherent Motion 

DWI and Dynamic Contrast-Enhanced MRI in Rectal Cancer", Computational and Mathematical Methods 

in Medicine, vol. 2021, Article ID 5095940, 7 pages, 2021. https://doi.org/10.1155/2021/5095940

50. Heliyon

Volume 9, Issue 5, May 2023, e16282

Journal home page for Heliyon

Research article

Prediction of prognostic factors in breast cancer: A noninvasive method utilizing histogram parameters derived from Adc maps

Özge Tanişman a, Fatma Tuba Kiziltepe b, Çiğdem Yildirim c, Zehra Sumru Coşar b

https://doi.org/10.1016/j.heliyon.2023.e16282

51. Abdominal Radiology  Article

Hepatobiliary

Published: 20 August 2021

Whole tumor volumetric ADC analysis: relationships with histopathological differentiation of hepatocellular carcinoma

Ferhat Can Piskin, Huseyin Tugsan Balli, Kivilcim Eren Erdoğan, Sinan Sozutok & Kairgeldy Aikimbaev 

Abdominal Radiology volume 46, pages5180–5189 (2021)Cite this article

52. Home  European Archives of Oto-Rhino-Laryngology  Article

Rhinology

Published: 22 June 2022

Texture analysis of conventional magnetic resonance imaging and diffusion-weighted imaging for distinguishing sinonasal non-Hodgkin’s lymphoma from squamous cell carcinoma

Guo-Yi Su, Jun Liu, Xiao-Quan Xu, Mei-Ping Lu, Min Yin & Fei-Yun Wu 

European Archives of Oto-Rhino-Laryngology volume 279, pages5715–5720 (2022)Cite this article

53.  Front. Oncol., 07 September 2021

Sec. Genitourinary Oncology

Volume 11 - 2021 | https://doi.org/10.3389/fonc.2021.702116

Clinical and Radiological Features of Urachal Carcinoma and Infection

Shichao Li Xiaoyan Meng Ping Liang Cui Feng Yaqi Shen Daoyu Hu Zhen Li*

54. Clinical Radiology

Volume 76, Issue 11, November 2021, Pages 846-853

Clinical Radiology

Whole-lesion histogram analysis of mono-exponential and bi-exponential diffusion-weighted imaging in differentiating lung cancer from benign pulmonary lesions using 3 T MRI

Author links open overlay panelQ. Zhu, C. Ren, J.-J. Xu, M.-J. Li, H.-S. Yuan, X.-H. Wang

55. Front. Immunol., 15 April 2021

Sec. Multiple Sclerosis and Neuroimmunology

Volume 12 - 2021 | https://doi.org/10.3389/fimmu.2021.670646

PD-L1 Improves Motor Function and Alleviates Neuropathic Pain in Male Mice After Spinal Cord Injury by Inhibiting MAPK Pathway

Fanqi Kong1† Kaiqiang Sun1† Jian Zhu1† Fudong Li1† Feng Lin1 Xiaofei Sun1 Xi Luo1 Changzhen Ren3 Lantao Lu1 ShuJie Zhao2 Jingchuan Sun1* Yuan Wang1* Jiangang Shi1*

56. Gerhalter, T., Cloos, M., Chen, A.M. et al. 

T1 and T2 quantification using magnetic resonance fingerprinting in mild traumatic brain injury. Eur Radiol 32, 1308–1319 (2022). 

https://doi.org/10.1007/s00330-021-08235-8

57. Chen Wang, Jing Yu, Ming Lu, Yang Li, Hongyuan Shi, Qing Xu,

Diagnostic Efficiency of Diffusion Sequences and a Clinical Nomogram for Detecting Lymph Node Metastases from Rectal Cancer,

Academic Radiology,

Volume 29, Issue 9,

2022,

Pages 1287-1295,

ISSN 1076-6332,

https://doi.org/10.1016/j.acra.2021.10.009.

58.  X. He, J. Zhou, S. Ye, Q. Cheng, H. Miao, N. Xu, J. Li, Z. Pan, J. Cheng, M. Wang,

Differences in tumour heterogeneity based on dynamic contrast-enhanced MRI between tumour and peritumoural stroma for predicting Ki-67 status of invasive ductal carcinoma,

Clinical Radiology,

Volume 76, Issue 6,

2021,

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ISSN 0009-9260,

https://doi.org/10.1016/j.crad.2020.12.008.

59.  Tim J. van Oostenbrugge, Ilse M. Spenkelink, Louisa Bokacheva, Henry Rusinek, Martin J. van Amerongen, Johan F. Langenhuijsen, Peter F.A. Mulders, Jurgen J. Fütterer,

Kidney tumor diffusion-weighted magnetic resonance imaging derived ADC histogram parameters combined with patient characteristics and tumor volume to discriminate oncocytoma from renal cell carcinoma,

European Journal of Radiology,

Volume 145,

2021,

110013,

ISSN 0720-048X,

https://doi.org/10.1016/j.ejrad.2021.110013.

60.  Oncology Letters

Diagnostic value of MRI radiomics in differentiating high‑grade glioma from low‑grade glioma: A meta‑analysis

Authors: Jiefang Wang Zhichao Chen Jieyun Chen

Published online on: August 23, 2023     https://doi.org/10.3892/ol.2023.14023

61. Lu, J., Li, Y., Li, Y.A. et al. 

In vivo detection of dysregulated choline metabolism in paclitaxel-resistant ovarian cancers 

with proton magnetic resonance spectroscopy. 

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62. Rezaeijo, S.M., Hashemi, B., Mofid, B. et al. 

The feasibility of a dose painting procedure to treat prostate cancer based on 

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63. Yitong Li, Yan Xiong, Bowen Hou, Chanyuan Liu, Jingyi Wang, John N. Morelli, Shuang Hu, Yao Zhang, Dong Sun, Xiaoming Li,

Detection of erosions and fat metaplasia of the sacroiliac joints in patients with suspected sacroiliitis using a chemical shift-encoded sequence (IDEAL-IQ),

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A systematic review of radiomics in pancreatitis: applying the evidence level rating

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65. Research Article

Greater hypothalamic microglial activation with aging in women as 

compared to men: potential relevance to sex and species differences in reproductive and biologic aging.

Tracy Butler, Lidia Glodzik, Xiuyuan Hugh Wang, Ke Xi, Yi Li, and 15 more

This is a preprint; 

https://doi.org/10.21203/rs.3.rs-1538708/v1

66. Han, Q., Lu, Y., Wang, D. et al. Assessment of dynamic hepatic and renal imaging 

changes in COVID-19 survivors using T1 mapping and IVIM-DWI. 

Abdom Radiol 47, 1817–1827 (2022). https://doi.org/10.1007/s00261-022-03471-y

67. Front. Oncol., 01 December 2022

Sec. Cancer Imaging and Image-directed Interventions

Volume 12 - 2022 | https://doi.org/10.3389/fonc.2022.882584

Practical nomogram based on comprehensive CT texture analysis to preoperatively predict peritoneal occult metastasis of gastric cancer patients

Shuxiang Chen1* Huijuan Zhang1† Hong Wei2† Yongxiu Tong1 Xiaofang Chen1

68. Jing Lu, Hai Ming Li, Song Qi Cai, Shu Hui Zhao, Feng Hua Ma, Yong Ai Li, Xiao Liang Ma, Jin Wei Qiang,

Prediction of Platinum-based Chemotherapy Response in Advanced High-grade Serous Ovarian Cancer: ADC Histogram Analysis of Primary Tumors,

Academic Radiology,

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69. Altinmakas, E., Bane, O., Hectors, S.J. et al. 

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72. Su, Guo-Yi, et al. "Texture analysis of diffusion kurtosis imaging for 

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73. Pan, Ting, et al. "Combined texture analysis of dynamic contrast-enhanced MRI with 

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78. Luo, Ban, et al. "Correlation Analysis between Intraocular Pressure and Extraocular 

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80. Xia, Wei, et al. "Quantitative T2 mapping magnetic resonance imaging of articular cartilage 

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81. Lotan, Eyal, et al. 

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82. Li, Haiming, et al. 

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 Build 432 is released.

1. Model #19 (ADC): in case when only 2 timepoints are present, check that Y[0]>Y[1], otherwise set the voxel to VOIDVOX. Defect was negative ADC values.

2. Implemented an initial version of GoRe : technology to produce smooth parametric maps.

3. Moved Brain segmentation function from MainMenu>Segment   to  Workflows>BrainMR.

 Build 431A is released.

1. Batch module report correction (NIH tag fix)

 Build 431 was released.

1. Implemented Batch module for fixing DICOM tags in the folder as per NIH instructions.

Build 430A is released.

 1. Radiomics Batch is changed so both REAL and INT volume could be processed in one batch.

2.  Added the WorkSizeCM3 measurement for Radiomics Batch.

3. Radiomics Menu item re-arrangement.

Build 430 is released.

 1. Updated the model #18:  "Basic IVIM".

2. Implemented IVIM model #54 based on the "Whole  Solution Space" engine.

3. Model #53: Provided the conversion function from specified COD to RMSE so it is could be supplied as the SolEps to the Optimization (typical used COD value = 0.999)

4. Added the working resolution option for Radiomics2D : Individual\Batch processing.

TO ACTIVATE Radiomics2D for INT Maps:

1. Main Menu>Applications>Integer Map Batch Feature Analysis.

2. Dialog will appear to specify the folder (full of FVX files with several layers).

3. After short analysis a dialog box will appear which will show "various" for layer names.

4. At this point you can change the histogram binning common to all cases (fvx files).

5. Press "Features" to select the desire Radiomics features.

6. Note "Working Resolution (mm)" edit box.  Leave default "0" to process layers at their current resolution. 

OR Specify  a different working resolution. All images will be converted to the specified Isotropic resolution (this would not be shown to the User explicitly).

FireVoxel Build 429 is released.

1. Implemented GLDM Radiomics measures and modified the dialog correspondingly.

 Build 428C was released.

1.  Switch to qform=1 representation when saving NIFTI files.

Build 428B released.

1. NIFTI file save: corrected orientation problem when saving non-isotropic volumes.

Build 428A is released.

1. Corrected WML segmentation dialog (AlgoVer setting)

 Build 428 is released.

1. WML Segmentation : Algorithm selection is moved into the main dialog.

2. Removed the redundant "Inflate LV" field.  Now the same value as "Peel Cortex" is used.

3. WML Algo4:  fixed memory leaks.

FireVoxel Build 427 is released.

1. WML segmentation : Implemented batch job based on FVX files as a source.

2. Ground Truth evaluation batch on a set of FVX files.

3. New Algorithm (4) for WML segmentation based on WM\WML signal estimation.

4. WML segmentation : Fixed the crash when MPRAGE volume is used.

 Build 426 is released.

1. WML algorithm : expansion into BrightArea is removed.

2. WML algorithm : added option to keep the max Connected Component of WM (default = true)

 Build 425 is released.

1. WML algorithm corrections

2. Single version of algorithm (Algo2 ) is left.

3. Default parameter corrections.

Build 424 is released

 1. New optimization GOWSS engine is released that returns the entire solution space approximation.

2. Correction in EdgeWave "Mark Grow Start Voxels" function, removed the parallel_for construct.

3.  New EdgeWave function : GrowROIintoConstraint.

4. Implemented a new variant of WML segmentation (Algo2).

Build 423 is released.

 1. WML processing:  WM layer added to output as a new layer (both single and batch variants).

2. WML algorithm: changed the way the LVinfl is used. Now the GM mask generated explicitly, then LVinfl is subtracted from GM.

3. Re-arrangement of the WML dialog box.

4. WML : added a function to remove the brain stem

Build 422C is released.

 1. WML segmentation from FLAIR_MPRAGE : Algorithm corrections

Build 422B is released.

 1. WML batch : fixed the crash with non-standard Folder structure.

2. Fixed: Open recent file (.nii) : when the file is missing - crash.

3.  Updated the WML batch report,

4. Siemens custom parameter map scaling update.

 Build 422A released.

1. Updated the report output for WML batch using DICOMs.

Build 422 is released.

 1. Implemented initial version of WML batch processing from DICOM folders.

2. Corrected scaling of SIEMENS software maps in BM1 module.

Build 421 is released.

 1. Fixed the crash when Saving FvX file, the dialog press Cancel button.

2.  Fixed defect in EdgeWave algorithm, when running in 2D Mode. Defect was the empty mask because each slice was treated as 3D volume.

3. Implemented a prototype V1 of Heart Segmentation from CT.

4.  Implemented custom DICOM scaling when loading the parametric maps generated by Siemens software.

5.  Implemented File>Open Single DICOM File function.

 1. Expanded diagnostics messages when opening DICOM folder and no DICOM files are found.

2.  Corrected the tools BM1 and BM3 to accommodate the variety of parametric maps names.

Build 420A is released.

 1. Split multiframe DICOM file :  added logic when different frames can have different bits per pixel within the same DICOM file.

2. When "No DICOM files found" message appears it will also show the name of the folder.

Build 420 is released.

 1. Developed a tool to select only specified b-values from the folder with DICOM files.

2. Fixed crash defect in Volume>Crop function.

3. Extended the BM1 tool (creating DWI documents) to load multiple layers of the parametric maps.

4. Developed function "Split muti-frame DICOM folder".

 Build 419B is released.

1. Fixed error when loading b-values from DICOM files generated by SIEMENS\Prisma-fit

2. Open DICOM dialog: implemented a new feature that displays all b-values inside the DICOM tree.

3. Fixed crash defect in Workflows>Brain MR>White Matter lesions

Build 419A is released.

 1. BM1a tool (extract specified b-values from a folder of FVX files): fixed the defect and updated the UI.

2. Multiple Zones Concentric Objects (UI function) : simplified parameter dialog by removing the "Algorithm type". Now it is fixed to =3.

3. Removed the TPS option from the FLEXR 3D/MC transformation options.

Build 419 is released.

 1. Implemented a new distance-based algorithm for 2-border Zone Split (Concentric Objects)

2. BM1a module logic adjustments: after all Common and Uncommon values are selected, the User can choose from the whole b-value set (not just commons)

Build 418B is released

 1. Recompile application using Libtorch 2.0

2. Multiple zones concentric objects function : enable all 3 starting modes : {Inner,Outer,Dual}

Build 418A is released.

 Multiple Zone Concentric Objects segmentation :  Zone Indices start from [1, NumberOfZones]. This is done so when exporting this map to NIFTI value=0 could be chosen for transparency.

Build 418 is released.

 1. Implemented GUI level function : ROI>Multiple Zones Concentric Objects function.

2. Enabled loading of single slice 4D volumes where different timepoints have different orientation. A verification dialog pops up for the User.

Build 417D

 1. DICOMTreeToFolders function variants are now performing sorting of Images by TIME under each SERIES

2. ROI>Layer Peel function : added logic that for a single slice volumes the 2D variant is called. For multislice volumes the 3D variant is called.

 Build 417C is released.

1. DICOMTREE - to - FOLDERS tool:  if the valid b-value is present it is appended to the end of the file.

2. Ensured that the files withing the SERIES are sorted in their temporal acquisition order.

 Build 417B is released.

1. Batch tool BM1a is fixed so in multilayer FVX files all layers are moved to the Target documents.

Build 417A is released.

 1. Fixed memory leaks in Argazi 3D Edge detector.

2. Optimized the AddLayerByCloning function. This also fixed the memory leak (relevant to parametric map calculations).

Build 417 is released.

 1. Various Document Cropping function:  optimized API.

2, Volume>Crop Specified Dynamic points : fixed defect that input dynamic indices were treated

as time indices.

3. Implemented Initial variant of "Extract common b-values from the FVX folder"

4. Fixed memory leak in FVX document save (Memfile buffer)

5. Fixed memory leak in FVX document save (freeing CheckDoc document)

Build 416C is released.

 1. Fixed memory leak in INNCOMP.CPP\Int_BlockDecode.

2. Fixed memory leak in VolumeSupport.cpp\VolMinMax

3. Fixed defect when creating ImagePositionPatient tag during loading from non-DICOM image (f.e. NIFTI).

4. Fixed Memory leaks in Radiomics code.

Build 416B is released.

 1. Fixed an unwanted message when loading DICOM from an unknown Phillips scanner model.

2. Fixed the spaces in the Lung Report text.

3. Fixed a memory leak in EdgeWave function (1MB on MPRAGE brain).

Build 416 is released.

Re-engineering of the Workflow>Lung(MR)>Display Curves dialog box

1.  Implemented ability to change the Temporal resolution of the curves.

2.  Implemented "Show Left", "Show Right", "Synchronize" buttons.

3.  Fixed bug in Reporting the lung area and volume (cm2\cm3)

4. Parallelize the Diaphragm movement calculation to substantially speed up the Dialog opening.

5. Memory leak fixed  in CreateDICOMrecord function

Build 415A is released.

 1. Implemented the Memchecker tool for detecting Memory leaks with the full stack trace.

2. Updated the "Save to RAW" core functions. This fixed the error when loading the 4D DICOM and then saving it to NIFTI/.

3. Batch module BM2 : Fixed the situation when after auto processing each document a dialog box will pop-up and ask the user if the document has to be saved.

Build 415 is released.

 1. Extended DICOM heuristics for determining IsDicomFile: for the files without preamble\DCIM

2. When saving to FVX file: if a layer volume contains a slice which is fully VOID that was producing a crash.

3. Corrected saving to RAW formats (incl NII) when there re VoidVoxels and user chooses NAN as the replacement. There were numerous defects around it,

4. MainMenu>ROI>Clip Volume by ROI :corrected transparent value selection so the NAN is used to represent VOIDVOX (instead of incorrect -1 previously).

5. NIFTI Save: corrected the sform matrix calculation (to incorporate pixdim into the matrix).  Verified .NII overlay under ITK-Snap

6. Batch processing module BM2 :  corrected so the processed FVX file when reloaded is shown in the same default projection as before processing.

7. BM2 module crash is fixed.

8. Parallelize Hist64 calculation with x10+ speed increase.

FireVoxel Build 414A is released.

 1. Corrected MIDAS (.im) file loading so the Orientation is VOID instead of default (MIDAS file does not hold the orientation info).

2. BM1 module gives a dialog choice how to add the layers ROI layer in {DICOM,NIFTI} format.

3. Corrections and additions to the Pancreas Center line measurement report.

4. FireVoxel default PHI profile added RETIRED_OtherPatientsID

Build 414 is released.

 1. When calculating each slice "absolute time", changed the base year to Y2000 (to increase the time precision).

2. Rework of the NiftiToDicom function.

3. Rework of the Orientation functions.

4. Restored the DICOM TransferSyntax status display.

5. Enabled loading of the "3D Screen shot RGB"   CT volume.

Build 412A is released.

 1. Corrected formatting in FLEXR3D and FLEXRMC dialogs.

2. Update the Incoherence2 measure calculation, so the optimal value is measured in the first local minimum after the peak.

Build 412 is released.

 1. Implemented MainframeMenu>Dynamic Analysis>Display Single Curve.

2. When loading TAC from text file automatically (heuristically, there is not sure way) determine the encoding of the text file to be char(8) or TCHAR(16). Previous version treated all the files as char.

3. Developed Incoherence2 curve measure (without minimum period constant).

4. Implemented Multi-Column Curve loading function. This is available currently under "Display Single Curve" and "Single Curve Basic measurement" UI functions.

Build 411A is released.

 1. Fixed error in REAL : internal compression when the entire slice has the same value. This was causing a crash in "LoadTac as 4D" function.

2.Added an ABT subtest for the LoadTacAs4D function.

Build 411 is released.

 1. Implemented a new DICOM header compression scheme when stored in FVX files. 3rd party compression is phased out. There is no saving a temporary file into FireVoxel TEMP directory thus removing a host of problems.

2. FVX format v.16 is introduced.

3. New timings on compressed 500MB file (with highly compressed DICOM headers)

Build 410B:   Load=3.59 sec.                   Save:78 sec              Size:  499 MB (original 1,006 MB)

Build 411:      Load=3.29 sec                    Save: 15.8 sec          Size:   535 MB (original 1,006 MB)

4. Performed correction in MainMenu>ROI>Normalize by ROI function 

New function:

a) works both for INT and REAL volumes (old one INT only)

b) Both 3D and 4D (old one 3D only)

c) Has a progress indicator.

5. Removed irrelevant unsupported file formats from Image Save function dialog box.

Build 410B is released.

 1. BM1 (breast cancer project): implemented a supporting custom function for loading the DWI volume from a folder containing NIFTI files with b-values encoded in file names.

2. When compressing the DICOM headers inside the FVX file : added the "delete file" operation pre\post the operation. For some reason the 7zip.exe was failing occasionally if the previous compressed file was present in the Temp folder.

Build 410A is released.

 1. Addressed FireVoxel document Load|Save speed issues.

Build 410 is released.

 1. Compiled and link the latest DCMTK 3.6.7   as DLLs.  Static libs (non-DLL) linkage is not working at the moment. Posted a request at the developers forum.

2. Fvxdcm_DC.cpp : corrected the handling of  VR_AS and VR_UI.

3. Deep verification of FVX file save:  in addition to byte-for-byte comparison with the internal MemFile, we also reload the FVX document and compare it on the entity level.

4. FVX file now contains the Build# that created it.

5. Finally linked DCMTK 3.6.7 statically (by fixing CMake script defect)