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Thursday, February 27, 2014

Rewriting the Liver DCDI fit procedure, so the Amoeba optimization is performed many times from various starts in the grid, instead of a single start.
Implemented variant of Amoeba-local optimization that is guaranteed to stay within User-specified parameter bounds.  Applied it to the problematic liver case from Hersh. However, the obtained fit is not as good as for other cases, so continue the work on more efficient optimization procedure.  Here is current best result:


Further investigation of the fitting problems on Hersh's example:  very good fit is found by Amoeba,  but the best value is found is outside the acceptable physical range of parameters (f.e. the Arterial fraction is negative).  So clearly the Optimization procedure has to change in some way.  Investigations to continue.