Build 450 is released.

 1. DICOM Smoothing batch tool: performed correction for site#3 by folding STUDY UID.

2. Temporal Shape Means smoothing - implemented 2D option for a major acceleration.

3. Internal : Add Layer using Header Volume: fixed the crash defect when there was a mixture of 3D and 4D layers.

4. Neck Multimodality workflow: Updated the parameters for CT->GRASP FLEXR registration.