Idea is to capture the spatial characteristics of the tumor by detecting Texture-sensitive edges within the tumor at different scales and different apperture weights.

EMD texture edges, Scale=3, Apperture=constant

 Here are the corresponding Edge strength distribution histograms:  They have a widely varying StdDev/Mean and so on.

We can also Build the "Concentric Profiles" of Edge Strength distribution ( in corresponding order)