Preliminary result: Substantial registration improvement is achieved on Liver-GRASP-DCDI exam

 First, User contructs a fairly precise "Whole Liver ROI" on a single timepoint (SK,t=25).
This is done by outlining the liver on every 2nd slice and applying Fill&Morph operation (total time=5 min).  This Whole Liver ROI will be used in registration and further liver function evaluation.

ROI contours are manually drawn on Axial projection and simultaneously displayed on Coronal.

Before registration: SK-case, timepoint t=20, and the Target Liver ROI (t=25)

After registration: Anatomy and the Target ROI are aligned.

Parameter set that has been  used.