2CXM model was implemented using the    Simplex Optimization with Gridding

Initial setup contains ROI region (orange) and Arterrial Input Function  (blue).  It is displayed as concentration.

Fitting curves displayed as Concentration

Resulting fitting optimal parameters

BiCal on 4D images: implemented an option and the user interface for  "Static\Dynamic" field option when in "Static field" we perform BiCal only once on the starting timepoint and then apply the resulting field to the rest of the timepoints.

Whole Lever ROI was segmented on VIBE and.
Then GRASP was registered to   VIBE+ROI.
Note: BiCal non-uniformity correction on GRASP was critical.

GRASP case 01

GRASP case 02

Initial variant of fully automatic liver registration from VIBE abdominal MR.
This uses: BiCal, Edge Constrained Smooth, EdgeWave with Competitive Growth.

VIBE case 01

VIBE case 02

Implemented Foerstner landmark Keypoints for Large Deformation registration

Large deformation registration: Foerstner Operator map: fixed the situation when some voxel have numerical overflow.

FireVoxel  Build 251A is released.

Layer Control Dialog:  changed the logic so if no Layers are disabled then the Active layer is deleted with the warning.

Layer Control Dialog - fixed arbitrary Active layer change when switching between 2 documents.

Implemented an initial upgrade to EdgeWave:   EdgeWaveCG (with Competitive Growth option)
Below is comparison of current EdgeWave and EdgeWaveGC   with identical parameters  and seed.

conventional EdgeWave:  (0.9/3/5mm/8mm)

EdgeWave CG   (0.9,3,5mm,8mm)

FireVoxel Build 250 is released.

Re-engineered the FireVoxel under the latest VC++ 2017

Removed large legacy code related to a redundant BGR representation of colors parallel to the COLORREF (RGB) definition used by Windows.  This greatly simplifying the ROI display code.

Fixed the L\B-endian issue in the layer name when loading a RAW  MIDAS file.

FireVoxel Build 249B is released.

Layer Control dialog box:  fixed the "Invalid Layer Index" defect after removing several layers.

Implemented Foerstner Operator map generation.  This is used for the Automatic Landmark generation in Large Deformation Registration.  MainMenu>Segmentation>Foerstner Operator Map.

1.  LayerControl dialog: fixed defect when selection was arbitrarily change after activating ViewFilter function.

2. Fixed defect: when a layer is saved into a RAW file, its name is changed in layer control, but there is a latency in name display/.

Implemented an initial variant of the "Make Landmark to ROI Cone"  under  "Renal fat assessment workflow"

1.  Fixed the defect in the Multi file Layer load, when not able to load a single file.
2.  Corrected defects related to the "L\R-endian" info added to some layer names.  F.e. ABT
subtests on Dynamic framework were failing.