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Monday, January 27, 2014

Finalized the Gamma Variate fit of the arbitrary function.  Introduced the "Fit" operation of the TAC inside the RoiStats4D dialog.  Other fitting models will be gradually added.

Above example is done with the Integral L2 measure (so would work fine with uneven sampling).  Global Optimization was used (A,alpha,beta).

Clearly Gamma Variate does not have enough expressive power due to the 2 factors
  • Recirculation peak
  • Tail asymptomatic value is non-zero
Recently (ISMRM 2011)  AIF fitting with two Gamma Variate functions was introduced (once of the authors is Niels Osiegmann).

http://cds.ismrm.org/protected/11MProceedings/files/816.pdf



Implemented a function for Gamma-variate fit of the arbitrary function.
Global Optimization with 3-parameter fit is used.


Some applications include:

  • Modelling of the Input function
  • Segmentation of the 4D volume
  • Automatic IDIF finder.


Implementing a simple dialog and debugging...
Restoring the complete Automatic Build Test to reflect changes in .FVX format due to a recent change in the format.
Updated and restored .FVX format Load\Save due to a change in the basic volumetric entity data structure.
Defect corrected: when drawing with the paintbrush  on ROIs, when paintbrush crosses the right border of the image the drawn voxels would appear sometimes at the top border.